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For example, rodents, which are commonly used in animal studies, possess distinct lipid metabolism patterns compared to humans, potentially leading to discrepancies in the efficacy and safety profiles of metabolic modulators as research transitions from animal models to human applications (140)

Subjective evaluation of skin properties For global evaluation, at each visit, subjects were asked to grade the overall response using a 4-point rating scale: 4 = very satisfactory, 3 = moderately satisfactory, 2 = minimally satisfactory, and 1 = not satisfactory

San Diego, USA: Elsevier